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— Facial treatment · Barcelona
Dr. Bermejo Pérez · Reg. no. 63226
A collagen biostimulator with an immediate volumising effect. Calcium hydroxylapatite works in two phases — instant structural support and gradual tissue regeneration over months. The longest-lasting result among regenerative treatments.
In short
Calcium hydroxylapatite is a biostimulator that supports the skin and stimulates your own collagen to treat laxity. A 30–45 minute session, minimal downtime and results lasting 18–24 months. Price: €280–350 per vial. Treatment is performed by Dr. Rubén Bermejo Pérez, a registered aesthetic physician (COMB no. 63226), at Clínica Sagrada Família, Barcelona.
Dr. Bermejo explains the double role of calcium hydroxylapatite: a slight immediate lift and collagen production in the medium term.
Medical judgement
“Calcium hydroxylapatite doesn't choose between filling and regenerating. It does both — and that's why it lasts longer than any hyaluronic acid.”Dr. Rubén Bermejo Pérez
How it works · Calcium hydroxylapatite
A slight lift and new collagen.
They integrate into the deep dermis and give a small immediate lift.
They stimulate fibroblasts to produce new collagen.
The real result shows between three and six months.
Schematic illustration: microspheres are not to scale.
What it treats
Calcium hydroxylapatite gives immediate structural support where hyaluronic acid isn't dense enough to hold the tissue. In the cheek and midface it acts as scaffolding — restoring lost projection while stimulating collagen. The result is firmer and longer-lasting than with conventional fillers.
The skin of the neck and décolletage loses firmness and quality before the face — and responds less to conventional fillers. Diluted calcium hydroxylapatite stimulates collagen diffusely here, improving firmness and skin quality without adding volume. One of the few options with real results in these areas.
Hands age quickly and show volume loss very visibly — tendons, veins and bones become prominent. Calcium hydroxylapatite fills and firms the back of the hand with a very natural result that lasts longer than hyaluronic acid there.
For patients who have reached the limits of hyaluronic acid or want a more structural, lasting result, calcium hydroxylapatite is the most effective alternative. Its double action — immediate filling plus collagen stimulation — gives a duration no conventional filler can match.
The practical side
Everything you need to know before your consultation. No small print.
The longest duration among biostimulators. The collagen generated sustains part of the result beyond the product's absorption.
Including anaesthetic, application and immediate shaping. In most cases a single session is enough.
Possible swelling or mild bruising for 24–72 h. Normal life straight away. Avoid massaging the area for the first few days.
Where it's applied · Calcium hydroxylapatite
Treatment areas.
Restores volume lost at the temples.
Restores support and projection.
Defines the lower-face contour.
The areas are marked at the consultation and the product is applied with a cannula.
Who it's for
Not sure if it's for you? That is exactly what the consultation is for: I'll tell you honestly what I see.
Free first visit · no commitment
In the consultation we look at the proportions of your face, talk about what you want and set the goals together. If you don't need treatment, I'll tell you that too.
Frequently asked questions
Straight answers about calcium hydroxylapatite. If your question isn't here, write to me.
The price is €280–350 per vial, depending on the amount needed, confirmed at the assessment. The first consultation is free. You can see all fees on the prices page.
Usually 18–24 months — the longest among biostimulators. The collagen generated sustains part of the result beyond the product's absorption.
At Clínica Sagrada Família, C/ Torras i Pujalt 1 (3rd floor), Barcelona. It is performed personally by Dr. Rubén Bermejo Pérez, registered physician no. 63226.
Calcium hydroxylapatite (CaHA) is a mineral-based biostimulator — the same component that makes up bones and teeth. Injected into soft tissue it acts as scaffolding: it gives immediate support and stimulates your own collagen over the following months.
Hyaluronic acid only fills — when it's absorbed, the result disappears. Calcium hydroxylapatite fills and stimulates collagen at the same time. When it's absorbed, the collagen generated keeps part of the result. That's why it lasts 18–24 months versus 9–12 for hyaluronic acid. The trade-off is that it can't be reversed with hyaluronidase.
No. Unlike hyaluronic acid, it can't be dissolved with hyaluronidase. It is biodegradable — the body absorbs it naturally over 18–24 months. That's why patient selection and technique are especially important — there's no immediate way back if the result isn't as expected.
The volumising effect is immediate — visible from day one. Collagen stimulation is gradual and improves over the following 3–6 months. The final, most complete result shows at 3–4 months.
Discomfort is moderate — it's thicker than hyaluronic acid and the injection can create a little more pressure. We use local or topical anaesthetic depending on the area. Most patients tolerate it well.
Not everywhere. It's contraindicated in very thin skin — eyelids, lips, under the eyes — where the risk of irregularities or visible product is higher. The preferred areas are the cheeks, midface, neck, décolletage and hands.
In most cases a single session gives a complete result. After 18–24 months, when the effect starts to fade, the treatment can be repeated. Some patients with very marked volume loss may need a second session at 6 months.
Free consultation
First visit with no commitment. There is always an assessment first; if the treatment is right for you, it can be done the same day.
In Sant Gervasi, next to Ronda del General Mitre. It is not in the area around the Sagrada Família basilica.